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CYP2E1 Antikörper (AA 234-493)

CYP2E1 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3023079
  • Target Alle CYP2E1 Antikörper anzeigen
    CYP2E1 (Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1))
    Bindungsspezifität
    • 15
    • 11
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 234-493
    Reaktivität
    • 70
    • 51
    • 37
    • 15
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    Human
    Wirt
    • 77
    • 7
    • 3
    Kaninchen
    Klonalität
    • 74
    • 13
    Polyklonal
    Konjugat
    • 44
    • 12
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CYP2E1 Antikörper ist unkonjugiert
    Applikation
    • 64
    • 26
    • 19
    • 14
    • 13
    • 9
    • 9
    • 7
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    KVIKNVAEVK EYVSERVKEH HQSLDPNCPR DLTDCLLVEM EKEKHSAERL YTMDGITVTV ADLFFAGTET TSTTLRYGLL ILMKYPEIEE KLHEEIDRVI GPSRIPAIKD RQEMPYMDAV VHEIQRFITL VPSNLPHEAT RDTIFRGYLI PKGTVVVPTL DSVLYDNQEF PDPEKFKPEH FLNENGKFKY SDYFKPFSTG KRVCAGEGLA RMELFLLLCA ILQHFNLKPL VDPKDIDLSP IHIGFGCIPP RYKLCVIPRS
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 234-493 of human CYP2E1 (NP_000764.1).
    Isotyp
    IgG
    Top Product
    Discover our top product CYP2E1 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:50 - 1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid freeze / thaw cycles
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Ma, Zhu, Tan, Mao, Tang, Shen, Zhang, Kuang, Fei, Yang, Wang: "Gpr110 deficiency decelerates carcinogen-induced hepatocarcinogenesis via activation of the IL-6/STAT3 pathway." in: American journal of cancer research, Vol. 7, Issue 3, pp. 433-447, (2017) (PubMed).

  • Target
    CYP2E1 (Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1))
    Andere Bezeichnung
    CYP2E1 (CYP2E1 Produkte)
    Synonyme
    CYP2E1 antikoerper, CYP2E antikoerper, CYPIIE1 antikoerper, CPE1 antikoerper, P450-J antikoerper, P450C2E antikoerper, Cyp2e antikoerper, cytochrome P450, family 2, subfamily E, polypeptide 1 antikoerper, cytochrome P450 2E1 antikoerper, cytochrome P450 2E1-like antikoerper, cytochrome P450 family 2 subfamily E member 1 antikoerper, cytochrome P450, family 2, subfamily e, polypeptide 1 antikoerper, CYP2E1 antikoerper, PTRG_07411 antikoerper, LOC100342572 antikoerper, LOC100727914 antikoerper, LOC101843716 antikoerper, Cyp2e1 antikoerper
    Hintergrund
    This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.,CYP2E1,CPE1,CYP2E,P450-J,P450C2E,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Cytochromes,Lipid Metabolism,Cytochromes,Lipases,Drug metabolism,Cardiovascular,Lipids,CYP2E1
    Molekulargewicht
    56 kDa
    Gen-ID
    1571
    UniProt
    P05181
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