XRCC6/XRCC5 Antikörper (PE)

Produktnummer ABIN6933804

Produktdetails anti-XRCC6/XRCC5 Antikörper (PE)

Target: XRCC6/XRCC5 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5/6 (XRCC6/XRCC5))

Reaktivität: Human, Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser XRCC6/XRCC5 Antikörper ist konjugiert mit PE

Applikation: Immunofluorescence (IF), Flow Cytometry (FACS), Test (T)

Spezifität: Recognizes a dimer of two proteins of 70 kDa and ~80 kDa, identified as two subunits of Ku. MAb KU729 recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

Keine Kreuzreaktivität: Huhn, Maus, Ratte (Rattus)

Aufreinigung: Purified by Protein A/G

Immunogen: Nuclear extract of human HL-60 cells

Klon: KU729

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: Human cancer K562, HL-60, HEp-2 or HeLa cells.

Known Application: Flow Cytometry (5 µL per test per one million cells or 5 µL per 100 µL of whole blood),Immunofluorescence (1:50-1:100 for 30 minutes at RT),Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 100 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu XRCC6/XRCC5

Target: XRCC6/XRCC5 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5/6 (XRCC6/XRCC5))

Andere Bezeichnung: XRCC6 (p70) & XRCC5 (p80) (XRCC6/XRCC5 Produkte)

Molekulargewicht: 70kDa & 80kDa

Gen-ID: 2547, 7520

UniProt: P12956, P13010