XRCC6/XRCC5 Antikörper
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- Target Alle XRCC6/XRCC5 Produkte
- XRCC6/XRCC5 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5/6 (XRCC6/XRCC5))
- Reaktivität
- Human, Primate
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser XRCC6/XRCC5 Antikörper ist unkonjugiert
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Applikation
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
- Spezifität
- Human Ku70+Ku80 / XRCC6+XRCC5
- Keine Kreuzreaktivität
- Huhn, Maus, Ratte (Rattus)
- Aufreinigung
- Protein G purified
- Immunogen
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Nuclear extract of human HL-60 cells.
Type of Immunogen: Cells - Klon
- KU729
- Isotyp
- IgG1 kappa
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- Applikationshinweise
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Approved: Flo (0.5 - 1 μg/10 x106), ICC (0.25 - 0.5 μg/mL), IF (0.5 - 1 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL), IP
Usage: This antibody recognizes a dimer of two proteins of 70 kDa (Ku70) and ~80 kDa (Ku80), identified as two subunits of Ku. Antbody KU729 recognizes a conformational epitope of the Ku70 + Ku80 dimer, which is destroyed during Western blotting. The Ku70 + Ku80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis. Immunocytochemistry (Acetone-fixed cells) : 0.25-0.5 μg/mL for 30 minutes at RT. - Kommentare
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Target Species of Antibody: Human
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- PBS, pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2°C to 8°C.
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- Target
- XRCC6/XRCC5 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5/6 (XRCC6/XRCC5))
- Andere Bezeichnung
- Ku70+Ku80 / XRCC6+XRCC5 (XRCC6/XRCC5 Produkte)
- Hintergrund
- This antibody detects: Ku70+Ku80 / XRCC6+XRCC5
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