CRHR2 Antikörper (AA 51-150) (Cy3)

Produktnummer ABIN680776

Produktdetails anti-CRHR2 Antikörper (Cy3)

Target: CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))

Bindungsspezifität: AA 51-150

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRHR2 Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Spezifität: This antibody may cross react with CRHR1.

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CRHR2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CRHR2

Target: CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))

Andere Bezeichnung: CRHR2 (CRHR2 Produkte)

Synonyme: CRF-RB antikoerper, CRF2 antikoerper, CRFR2 antikoerper, HM-CRF antikoerper, CRF-R2 antikoerper, CRFR2alpha antikoerper, CRFR2beta antikoerper, Crfr2 antikoerper, Crf2r antikoerper, CRH-R2 antikoerper, crhr2-A antikoerper, corticotropin releasing hormone receptor 2 antikoerper, corticotropin releasing hormone receptor 2 S homeolog antikoerper, CRHR2 antikoerper, Crhr2 antikoerper, crhr2.S antikoerper

Hintergrund:

Synonyms: CRF2, CRFR2, CRF-RB, HM-CRF, Corticotropin-releasing factor receptor 2, CRF-R-2, CRF-R2, CRFR-2, Corticotropin-releasing hormone receptor 2, CRH-R-2, CRH-R2, CRHR2, CRF2R, CRH2R

Background: G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.

Gen-ID: 1395

UniProt: Q13324

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Feeding Behaviour