CRHR2 Antikörper (AA 10-39)

Produktnummer ABIN655389

Produktdetails anti-CRHR2 Antikörper

Target: CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))

Bindungsspezifität: AA 10-39

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRHR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CRFR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-39 amino acids from human CRFR2.

Klon: RB08932

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu CRHR2

Target: CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))

Andere Bezeichnung: CRFR2 (CRHR2 Produkte)

Synonyme: CRF-RB antikoerper, CRF2 antikoerper, CRFR2 antikoerper, HM-CRF antikoerper, CRF-R2 antikoerper, CRFR2alpha antikoerper, CRFR2beta antikoerper, Crfr2 antikoerper, Crf2r antikoerper, CRH-R2 antikoerper, crhr2-A antikoerper, corticotropin releasing hormone receptor 2 antikoerper, corticotropin releasing hormone receptor 2 S homeolog antikoerper, CRHR2 antikoerper, Crhr2 antikoerper, crhr2.S antikoerper

Hintergrund: Liaw et al. (1996) [PubMed 8536644] stated that there are 2 G protein-coupled corticotropin-releasing hormone (CRH, MIM 122560) receptors, CRHR1 (MIM 122561) and CRHR2, which they termed the CRF2 receptor. CRH is a 41-amino acid peptide synthesized in the hypothalamus that is the principal neuroregulator of the hypothalamic-pituitary-adrenocortical axis and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge.

Molekulargewicht: 47688

Gen-ID: 1395

NCBI Accession: NP_001189404, NP_001189410, NP_001189411, NP_001189412, NP_001874

UniProt: Q13324

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Feeding Behaviour