Angiotensin II Type-1 Receptor Antikörper (AA 201-300) (Cy5)

Produktnummer ABIN677517

Produktdetails anti-Angiotensin II Type-1 Receptor Antikörper (Cy5)

Target: Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))

Bindungsspezifität: AA 201-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Angiotensin II Type-1 Receptor Antikörper ist konjugiert mit Cy5

Applikation: Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Cow,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AT1R

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Angiotensin II Type-1 Receptor

Target: Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))

Andere Bezeichnung: Angiotensin II Type 1 Receptor (AGTR1 Produkte)

Synonyme: AG2S antikoerper, AGTR1A antikoerper, AGTR1B antikoerper, AT1 antikoerper, AT1AR antikoerper, AT1B antikoerper, AT1BR antikoerper, AT1R antikoerper, AT2R1 antikoerper, AT2R1A antikoerper, AT2R1B antikoerper, HAT1R antikoerper, 1810074K20Rik antikoerper, AI551199 antikoerper, AT1a antikoerper, Agtr-1a antikoerper, Agtr1 antikoerper, Angtr-1a antikoerper, AT1A antikoerper, XAT-1 antikoerper, agtr1-A antikoerper, agtr1.2 antikoerper, AT1-R antikoerper, at1 antikoerper, AGTR1 antikoerper, Agtr-1b antikoerper, Angtr-1b antikoerper, agtr1 antikoerper, agtr1-a antikoerper, agtr1-b antikoerper, xAT antikoerper, angiotensin II receptor type 1 antikoerper, angiotensin II receptor, type 1a antikoerper, angiotensin II receptor type 1 S homeolog antikoerper, uncharacterized AGTR1 antikoerper, angiotensin II receptor, type 1b antikoerper, angiotensin II receptor type 1 L homeolog antikoerper, AGTR1 antikoerper, Agtr1a antikoerper, agtr1.S antikoerper, Agtr1 antikoerper, Agtr1b antikoerper, agtr1.L antikoerper

Hintergrund:

Synonyms: AG2S, Agtr 1, Agtr1, Agtr1a, AGTR1B, Angiotensin II receptor type 1, Angiotensin II type 1 receptor, AT-1B, AT-1r, AT1, At1a, AT1AR, AT1B, AT1BR, AT2R1, AT2R1A, AT2R1B, HAT1R, Type 1 angiotensin II receptor, AGTR1_HUMAN, Type-1 angiotensin II receptor, Angiotensin II type-1 receptor, AT1R, Ang II, Angiotensin II receptor type 1, Angiotensin II type 1 receptor, Angiotensin receptor 1, Angiotensin receptor 1B, AT 1B, AT1, AT1R.

Background: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed, however, it is now believed that there is only one type 1 receptor gene in humans. At least five transcript variants have been described for this gene. Additional variants have been described but their full-length nature has not been determined. The entire coding sequence is contained in the terminal exon and is present in all transcript variants. [provided by RefSeq].

Gen-ID: 185

UniProt: P30556

Pathways: JAK-STAT Signalweg, ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour