SCNN1B Antikörper (C-Term)

Produktnummer ABIN6736428

Produktdetails anti-SCNN1B Antikörper

Target: SCNN1B (Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Affe, Ziege, Fledermaus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCNN1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marke: IHC-plus™

Spezifität: Human SCNN1B

Homologie: Percent identity by BLAST analysis: Human, Bovine, Goat (100%) Horse, Guinea pig (92%) Mouse, Rat (85%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide from C-Terminus of human SCNN1B (P51168, NP_000327). Percent identity by BLAST analysis: Human, Gibbon, Monkey, Galago, Goat, Elephant, Bovine, Bat, Opossum (100%), Gorilla, Rabbit, Horse, Guinea pig, Platypus (92%), Mouse, Rat, Hamster (85%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (2.5 μg/mL), WB (0.12 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 2.5 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Distilled water

Konzentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Details zu SCNN1B

Target: SCNN1B (Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B))

Andere Bezeichnung: SCNN1B / ENaC Beta (SCNN1B Produkte)

Synonyme: BESC1 antikoerper, ENaCb antikoerper, ENaCbeta antikoerper, SCNEB antikoerper, RNENACB antikoerper, besc1 antikoerper, betaxENaC antikoerper, enacb antikoerper, enacbeta antikoerper, scnn1b antikoerper, beta-ENaC antikoerper, scneb antikoerper, SCNN1B antikoerper, BETA-ENAC antikoerper, sodium channel epithelial 1 beta subunit antikoerper, sodium channel, non voltage gated 1 beta subunit L homeolog antikoerper, sodium channel, non voltage gated 1 beta subunit antikoerper, sodium channel, nonvoltage-gated 1 beta antikoerper, sodium channel, non voltage gated 1 beta subunit S homeolog antikoerper, SCNN1B antikoerper, Scnn1b antikoerper, scnn1b.L antikoerper, scnn1b antikoerper, scnn1b.S antikoerper

Hintergrund: Name/Gene ID: SCNN1B
Subfamily: Sodium channel - amiloride-sensitive
Family: Ion Channel

Synonyms: SCNN1B, BESC1, Beta-NaCH, Beta ENaC, Beta-ENaC, ENaC beta, ENaCb, HENaC, Liddle syndrome, RENaC, RNENACB, SCNEB, ENaCbeta

Gen-ID: 6338

NCBI Accession: NP_000327

UniProt: P51168