Macrophage Mannose Receptor 1 Antikörper (APC)
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- Target Alle Macrophage Mannose Receptor 1 (MRC1) Antikörper anzeigen
- Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))
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Reaktivität
- Maus
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser Macrophage Mannose Receptor 1 Antikörper ist konjugiert mit APC
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Applikation
- Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)
- Klon
- C068C2
- Isotyp
- IgG2a, kappa
- Top Product
- Discover our top product MRC1 Primärantikörper
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- Applikationshinweise
- Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].
- Kommentare
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Matching Isotype Control: APC Rat IgG2a, κ Isotype Control (ABIN7469841)
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.2 mg/mL
- Buffer
- PBS with 0.05 % Proclin300, 1 % BSA
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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- Target
- Macrophage Mannose Receptor 1 (MRC1) (Mannose Receptor, C Type 1 (MRC1))
- Andere Bezeichnung
- CD206 (MRC1 Produkte)
- Synonyme
- CD206 antikoerper, CLEC13D antikoerper, CLEC13DL antikoerper, MMR antikoerper, MRC1L1 antikoerper, bA541I19.1 antikoerper, AW259686 antikoerper, MR antikoerper, mrc1 antikoerper, MGC86525 antikoerper, MRC1 antikoerper, MRC1L-A antikoerper, mannose receptor C-type 1 antikoerper, mannose receptor, C type 1 antikoerper, mannose receptor C-type 1 L homeolog antikoerper, mediator of replication checkpoint 1 antikoerper, MRC1 antikoerper, Mrc1 antikoerper, mrc1.L antikoerper, mrc1 antikoerper
- Hintergrund
- MMR,MR,MRC1,macrophage mannose receptor,mannose receptor,CD206, also known as mannose receptor (MR), is a 175 kD type I membrane protein. It is a pattern recognition receptor (PRR) belonging to the C-type lectin superfamily. MR is expressed on macrophages, dendritic cells, Langerhans cells, and hepatic or lymphatic endothelial cells. MR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine through its C-type lectin-like carbohydrate recognition domains, sulfated carbohydrate antigens through its cysteine-rich domain, and collagens through its fibronectin type II domain. MR mediates endocytosis and phagocytosis as well as activation of macrophages and antigen presentation. It plays an important role in host defense and provides a link between innate and adaptive immunity. Recently, MR on lymphatic endothelial cells was found to be involved in leukocyte trafficking and a contributor to the metastatic behavior of cancer cells. It suggests that MR may be a potential target in controlling inflammation and cancer metastasis by targeting the lymphatic vasculature.
- Gen-ID
- 17533
- UniProt
- Q61830
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