PD-L1 Antikörper
-
- Target Alle PD-L1 Antikörper anzeigen
- PD-L1 (CD274 (PD-L1))
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser PD-L1 Antikörper ist unkonjugiert
-
Applikation
- Flow Cytometry (FACS)
- Aufreinigung
- Purified
- Klon
- 29E-2A3
- Isotyp
- IgG2b, kappa
- Top Product
- Discover our top product PD-L1 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
-
Matching Isotype Control: Purified Mouse IgG2b, κ Isotype Control (ABIN7469802)
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 0.5 mg/mL
- Buffer
- PBS with 0.05 % Proclin300
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2~8°C. Do not freeze.
-
- Target
- PD-L1 (CD274 (PD-L1))
- Andere Bezeichnung
- PD-L1 (PD-L1 Produkte)
- Synonyme
- B7-H antikoerper, B7H1 antikoerper, PD-L1 antikoerper, PDCD1L1 antikoerper, PDCD1LG1 antikoerper, PDL1 antikoerper, A530045L16Rik antikoerper, B7h1 antikoerper, Pdcd1l1 antikoerper, Pdcd1lg1 antikoerper, Pdl1 antikoerper, RGD1566211 antikoerper, CD274 molecule antikoerper, CD274 antigen antikoerper, programmed cell death 1 ligand 2 antikoerper, CD274 antikoerper, Cd274 antikoerper, PDCD1LG2 antikoerper
- Hintergrund
- B7-H1, PD-L1,Programmed cell death ligand 1,B7 homolog 1,B7-H, B7H1, PDL1, PDCD1L1, PDCD1LG1,CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells.
- Gen-ID
- 29126
- UniProt
- Q9NZQ7
- Pathways
- Cancer Immune Checkpoints
-