COL17A1 Antikörper

Produktnummer ABIN6719519

Produktdetails anti-COL17A1 Antikörper

Target: COL17A1 (Collagen, Type XVII, alpha 1 (COL17A1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COL17A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Collagen XVII/COL17A1 detection. Tested with WB in Human.

Sequenz: KVFSAYSNVT ADLMDFFQTY GAIQ

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Collagen XVII/COL17A1 detection. Tested with WB in Human.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence of human Collagen XVII/COL17A1(KVFSAYSNVTADLMDFFQTYGAIQ).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Application details: Western blot|0.1-0.5 μg/mL

Kommentare:

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu COL17A1

Target: COL17A1 (Collagen, Type XVII, alpha 1 (COL17A1))

Andere Bezeichnung: COL17A1 (COL17A1 Produkte)

Synonyme: col17a1 antikoerper, fk89a06 antikoerper, si:ch211-223p8.6 antikoerper, wu:fk89a06 antikoerper, COL17A1 antikoerper, BA16H23.2 antikoerper, BP180 antikoerper, BPA-2 antikoerper, BPAG2 antikoerper, LAD-1 antikoerper, Bpag antikoerper, Bpag2 antikoerper, collagen type XVII alpha 1 chain antikoerper, collagen, type XVII, alpha 1b antikoerper, collagen, type XVII, alpha 1 antikoerper, Col17a1 antikoerper, col17a1b antikoerper, COL17A1 antikoerper

Hintergrund:

Synonyms: Collagen alpha-1(XVII) chain, 180 kDa bullous pemphigoid antigen 2, Bullous pemphigoid antigen 2, 120 kDa linear IgA dermatosis antigen, Linear IgA disease antigen 1, LAD-1, 97 kDa linear IgA bullous dermatosis antigen, 97 kDa LAD antigen, 97-LAD, Linear IgA bullous disease antigen of 97 kDa, LABD97, COL17A1, BP180, BPAG2

Background: Collagen XVII, previously called BP180, is a transmembrane protein which plays a critical role in maintaining the linkage between the intracellular and the extracellular structural elements involved in epidermal adhesion. It is mapped to 10q25.1. This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form.

Gen-ID: 1308