ARPC1B Antikörper (AA 293-372)

Produktnummer ABIN6719390

Produktdetails anti-ARPC1B Antikörper

Target: ARPC1B (Actin Related Protein 2/3 Complex, Subunit 1B, 41kDa (ARPC1B))

Bindungsspezifität: AA 293-372

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARPC1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for ARP2/3 subunit 1B/ARPC1B detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for ARP2/3 subunit 1B/ARPC1B detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human ARP2/3 subunit 1B/ARPC1B recombinant protein (Position: Q293-K372).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Application details: Western blot|0.1-0.5 μg/mL Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL Direct ELISA|0.1-0.5 μg/mL

Kommentare:

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu ARPC1B

Target: ARPC1B (Actin Related Protein 2/3 Complex, Subunit 1B, 41kDa (ARPC1B))

Andere Bezeichnung: ARPC1B (ARPC1B Produkte)

Synonyme: ARC41 antikoerper, p40-ARC antikoerper, p41-ARC antikoerper, cb871 antikoerper, arpc1a antikoerper, fj15h02 antikoerper, zgc:64056 antikoerper, wu:fj08e12 antikoerper, wu:fj15h02 antikoerper, 41kDa antikoerper, AA408064 antikoerper, AA408534 antikoerper, AA571392 antikoerper, AF007010 antikoerper, AW208418 antikoerper, L72 antikoerper, SOP2Hs antikoerper, ACTIN-RELATED PROTEIN C1 antikoerper, ARPC1 antikoerper, F16D14.14 antikoerper, F16D14_14 antikoerper, actin-related protein C1B antikoerper, arc41 antikoerper, p40-arc antikoerper, p41-arc antikoerper, actin related protein 2/3 complex subunit 1B antikoerper, actin related protein 2/3 complex, subunit 1B antikoerper, ARP2/3 complex 41 kDa subunit antikoerper, actin-related protein C1B antikoerper, actin-related protein 2/3 complex subunit 1B antikoerper, actin related protein 2/3 complex subunit 1B S homeolog antikoerper, ARPC1B antikoerper, Arpc1b antikoerper, EHI_094120 antikoerper, arpc1b antikoerper, LOC100410640 antikoerper, arpc1b.S antikoerper

Hintergrund:

Synonyms: Actin-related protein 2/3 complex subunit 1B, Arp2/3 complex 41 kDa subunit, p41-ARC, ARPC1B, ARC41

Background: Actin-related protein 2/3 complex subunit 1B is a protein that in humans is encoded by the ARPC1B gene. It is mapped to 7q22.1. This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase.

Gen-ID: 10095

UniProt: O15143

Pathways: RTK Signalweg, Regulation of Actin Filament Polymerization