Adamts2 Antikörper (C-Term)

Produktnummer ABIN6657530

Produktdetails anti-Adamts2 Antikörper

Target: Adamts2 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 2 (Adamts2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Adamts2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Aufreinigung: Anti-ADAMTS2 antibody is directed against human ADAMTS2 protein.  The product was affinity purified from monospecific antiserum by immunoaffinity purification.  A BLAST analysis was used to suggest reactivity with this protein from human, mouse, and rat based on homology for the immunogen sequence.  Cross reactivity with ADAMTS2 from other sources has not been determined.

Immunogen:

Immunogen: ADAMTS2 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a sequence at the C-terminal of human ADAMTS2.

Immunogen Type: Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry Dilution: 1:100-1:500

Application Note: Anti-ADAMTS2 is useful for Immunohistochemistry -P, -F, and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~134.8 kDa corresponding to the appropriate cell lysate or extract.

Western Blot Dilution: 0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution:

Reconstitution Volume: 100 μL

Reconstitution Buffer: Restore with deionized water (or equivalent)

Buffer:

Buffer: 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide

Stabilizer: 5 mg BSA

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: RT,4 °C,-20 °C

Informationen zur Lagerung: Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Details zu Adamts2

Target: Adamts2 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 2 (Adamts2))

Andere Bezeichnung: ADAMTS2 (Adamts2 Produkte)

Synonyme: ADAM-TS2 antikoerper, ADAMTS-2 antikoerper, ADAMTS-3 antikoerper, PCINP antikoerper, hPCPNI antikoerper, mKIAA4060 antikoerper, pNPI antikoerper, NPI antikoerper, PC I-NP antikoerper, PCI-NP antikoerper, PCPNI antikoerper, PNPI antikoerper, RGD1565950 antikoerper, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2 antikoerper, ADAM metallopeptidase with thrombospondin type 1 motif 2 antikoerper, ADAM metallopeptidase with thrombospondin type 1 motif, 2 antikoerper, Adamts2 antikoerper, ADAMTS2 antikoerper

Hintergrund:

Synonyms: Procollagen I N-proteinase,

Background: ADAMTS2, A disintegrin and metalloproteinase with thrombospondin motifs 2, also known as procollagen I N-proteinase (PC I-NP), is an enzyme that in humans is encoded by the ADAMTS2 gene. The ADAMTS2 gene contains 22 exons. The human ADAMTS2 gene is mapped to chromosome 5q23-q24 by analysis of somatic cell hybrids. ADAMTS2 is responsible for processing several types of procollagen proteins. Procollagens are the precursors of collagens, the proteins that add strength and support to many body tissues. Specifically, this enzyme clips a short chain of amino acids off one end of the procollagen. This clipping step is necessary for collagen molecules to function normally and assemble into fibrils outside cells. This antibody is suitable for researchers interested in signal transduction, extracellular matrix antibodies and cancer research.

Gene Name: ADAMTS2

Gen-ID: 9509

NCBI Accession: NP_055059

UniProt: O95450