KCNQ4 Antikörper (N-Term)

Produktnummer ABIN6656738

Produktdetails anti-KCNQ4 Antikörper

Target: KCNQ4 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser KCNQ4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Fluorescence Microscopy (FM)

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Aufreinigung: Anti-KCNQ4 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with KCNQ4 from Human, Rat, and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity with KCNQ4 from other sources has not been determined. Channels and Transporters research.

Immunogen:

Immunogen: KCNQ4 Antibody was produced in mice by repeated immunizations raised against a fusion protein n-terminal region of human KCNQ4.

Immunogen Type: Peptide

Klon: S43-6

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

Immunohistochemistry Dilution: 0.1-1.0 μg/mL

Application Note: Anti-KCNQ4 Antibody is suitable for use in WB, IP, and IF microscopy. Expect a band approximately ~77 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Western Blot Dilution: 1-10 μg/mL

IF Microscopy Dilution: 1.0-10 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Lagerung: RT,4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Details zu KCNQ4

Target: KCNQ4 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4))

Andere Bezeichnung: KCNQ4 (KCNQ4 Produkte)

Synonyme: KCNQ4 antikoerper, k(v)7.4 antikoerper, kv7.4 antikoerper, DFNA2 antikoerper, DFNA2A antikoerper, KV7.4 antikoerper, potassium voltage-gated channel subfamily Q member 4 antikoerper, potassium channel, voltage gated KQT-like subfamily Q, member 4 antikoerper, potassium voltage-gated channel, subfamily Q, member 4 antikoerper, KCNQ4 antikoerper, kcnq4 antikoerper, Kcnq4 antikoerper

Hintergrund:

Synonyms: DFNA2, KQT like 4, Kv7.4, voltage gated potassium channel subunit Kv7.4, IKs producing slow voltage-gated potassium channel subunit alpha, KvLQT4, KQT-like 4, Potassium voltage-gated channel subfamily KQT member 4

Background: Specifically, the protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anticonvulsant drug.

Gene Name: KCNQ4

Gen-ID: 9132

NCBI Accession: NP_004691

UniProt: P56696

Pathways: Sensory Perception of Sound