SMARCA5 Antikörper

Produktnummer ABIN6655221

Produktdetails anti-SMARCA5 Antikörper

Target: SMARCA5 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SMARCA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Fluorescence Microscopy (FM)

Aufreinigung: Anti-hSNF2H was clarified from mouse ascitic fluid and is specific for hSNF2H.

Immunogen:

Immunogen: Anti-hSNF2H Antibody was produced in mice by repeated immunization with a recombinant protein of human SNF2H.

Immunogen Type: Recombinant Protein

Anwendungsinformationen

Applikationshinweise:

Application Note: Anti-hSNF2H Antibody is suitable for Immunofluorescence, Immunoprecipitation and Western Blots. Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 121.9 kDa in the appropriate cell lysate or extract.

Immunoprecipitation Dilution: 1 μg/IP

Western Blot Dilution: 1:1,000

IF Microscopy Dilution: 1:100 - 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Stabilizer: None

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: RT,4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Details zu SMARCA5

Target: SMARCA5 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A, Member 5 (SMARCA5))

Andere Bezeichnung: hSNF2H (SMARCA5 Produkte)

Synonyme: fb26d12 antikoerper, fb49g04 antikoerper, chunp6878 antikoerper, im:7146484 antikoerper, wu:fb26d12 antikoerper, wu:fb49g04 antikoerper, zgc:158434 antikoerper, smarca5 antikoerper, iswi antikoerper, SMARCA5 antikoerper, hiswi antikoerper, snf2h antikoerper, hsnf2h antikoerper, wcrf135 antikoerper, MGC79455 antikoerper, ISWI antikoerper, SNF2H antikoerper, WCRF135 antikoerper, hISWI antikoerper, hSNF2H antikoerper, 4933427E24Rik antikoerper, D030040M08Rik antikoerper, D330027N15Rik antikoerper, MommeD4 antikoerper, Snf2h antikoerper, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 antikoerper, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 S homeolog antikoerper, smarca5 antikoerper, smarca5.S antikoerper, SMARCA5 antikoerper, Smarca5 antikoerper

Hintergrund:

Synonyms: mouse anti-hSNF2H Antibody, mouse anti-SNF2H Antibody, mouse anti-Sucrose nonfermenting protein 2 homolog antibody, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin A5, Sucrose nonfermenting protein 2 homolog

Background: Complexes containing Snf2h (SMARCA5) are capable of forming ordered nucleosome arrays on chromatin in vitro (may require intact histone H4 tails). SNF2h is also required for replication of pericentric heterochromatin in S-phase, specifically in conjunction with BAZ1A. Snf2h probably also plays a role in repression of polI dependent transcription of the rDNA locus, through the recruitment of the SIN3/HDAC1 corepressor complex to the rDNA promoter. Snf2h is a catalytic subunit of the four known chromatin-remodeling complexes: CHRAC, RSF, ACF/WCRF, and WICH. Each complex contains subunits which may regulate the specificity or catalytic activity of SMARCA5. Snf2h possesses intrinsic ATP-dependent nucleosome remodelling activity. Anti-hSNF2H Antibody is ideal for research in Chromatin Remodeling, Epigenetics and Gene Expression.

Gene Name: SMARCA5

Gen-ID: 8467

NCBI Accession: NP_003592

UniProt: O60264

Pathways: Chromatin Binding