RP2 Antikörper (AA 244-348)

Produktnummer ABIN6654138

Produktdetails anti-RP2 Antikörper

Target: RP2 (Retinitis Pigmentosa 2 (X-Linked Recessive) (RP2))

Bindungsspezifität: AA 244-348

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity purified

Immunogen: Amino acids D244-M348 from the human protein were used as the immunogen for the RP2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the RP2 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL (human recombinant protein)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the RP2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu RP2

Target: RP2 (Retinitis Pigmentosa 2 (X-Linked Recessive) (RP2))

Andere Bezeichnung: RP2 / XRP2 (RP2 Produkte)

Synonyme: Rp2h antikoerper, RGD1565124 antikoerper, RP2 antikoerper, wu:fj10e02 antikoerper, wu:fm72d05 antikoerper, zfrp2 antikoerper, zgc:55632 antikoerper, DELXp11.3 antikoerper, NM23-H10 antikoerper, NME10 antikoerper, TBCCD2 antikoerper, XRP2 antikoerper, AI662636 antikoerper, Rp2 antikoerper, RP2, ARL3 GTPase activating protein antikoerper, XRP2 protein antikoerper, XRP2-like protein antikoerper, retinitis pigmentosa 2 (X-linked recessive) antikoerper, RP2, ARL3 GTPase activating protein S homeolog antikoerper, retinitis pigmentosa 2 homolog antikoerper, Rp2 antikoerper, RP2 antikoerper, Bm1_36735 antikoerper, PITG_13367 antikoerper, LOAG_11813 antikoerper, rp2 antikoerper, rp2.S antikoerper

Hintergrund: Protein XRP2 is a protein that in humans is encoded by the RP2 gene. It is mapped to Xp11.3. The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration may therefore be due to the accumulation of incorrectly folded photoreceptor or neuron-specific tubulin isoforms followed by progressive cell death. The RP2 protein is also involved in regulating the function and extension of outer segment of cone photoreceptors in mice.

UniProt: O75695

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process