RP2 Antikörper (AA 244-348)

Produktnummer ABIN6719513

Produktdetails anti-RP2 Antikörper

Target: RP2 (Retinitis Pigmentosa 2 (X-Linked Recessive) (RP2))

Bindungsspezifität: AA 244-348

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for RP2 detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for RP2 detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human RP2 recombinant protein (Position: D244-M348).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Application details: Western blot|0.1-0.5 μg/mL Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL Direct ELISA|0.1-0.5 μg/mL

Kommentare:

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu RP2

Target: RP2 (Retinitis Pigmentosa 2 (X-Linked Recessive) (RP2))

Andere Bezeichnung: RP2 (RP2 Produkte)

Synonyme: Rp2h antikoerper, RGD1565124 antikoerper, RP2 antikoerper, wu:fj10e02 antikoerper, wu:fm72d05 antikoerper, zfrp2 antikoerper, zgc:55632 antikoerper, DELXp11.3 antikoerper, NM23-H10 antikoerper, NME10 antikoerper, TBCCD2 antikoerper, XRP2 antikoerper, AI662636 antikoerper, Rp2 antikoerper, RP2, ARL3 GTPase activating protein antikoerper, XRP2 protein antikoerper, XRP2-like protein antikoerper, retinitis pigmentosa 2 (X-linked recessive) antikoerper, RP2, ARL3 GTPase activating protein S homeolog antikoerper, retinitis pigmentosa 2 homolog antikoerper, Rp2 antikoerper, RP2 antikoerper, Bm1_36735 antikoerper, PITG_13367 antikoerper, LOAG_11813 antikoerper, rp2 antikoerper, rp2.S antikoerper

Hintergrund:

Synonyms: Protein XRP2, RP2

Background: Protein XRP2 is a protein that in humans is encoded by the RP2 gene. It is mapped to Xp11.3. The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration may therefore be due to the accumulation of incorrectly folded photoreceptor or neuron-specific tubulin isoforms followed by progressive cell death. The RP2 protein is also involved in regulating the function and extension of outer segment of cone photoreceptors in mice.

Gen-ID: 6102

UniProt: O75695

Pathways: Nucleotide Phosphorylation, Ribonucleoside Biosynthetic Process