PKMYT1 Antikörper (N-Term)

Produktnummer ABIN657999

Produktdetails anti-PKMYT1 Antikörper

Target: PKMYT1 (Protein Kinase, Membrane Associated tyrosine/threonine 1 (PKMYT1))

Bindungsspezifität: AA 114-143, N-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKMYT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This Mouse Pkmyt1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-143 amino acids from the N-terminal region of mouse Pkmyt1.

Klon: RB34667

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Mouse Pkmyt1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Haltbarkeit: 6 months

Details zu PKMYT1

Target: PKMYT1 (Protein Kinase, Membrane Associated tyrosine/threonine 1 (PKMYT1))

Andere Bezeichnung: Pkmyt1 (PKMYT1 Produkte)

Synonyme: MYT1 antikoerper, 6230424P17 antikoerper, AW209059 antikoerper, Myt1 antikoerper, RGD1305434 antikoerper, myt1 antikoerper, protein kinase, membrane associated tyrosine/threonine 1 antikoerper, protein kinase, membrane associated tyrosine/threonine 1 S homeolog antikoerper, PKMYT1 antikoerper, pkmyt1 antikoerper, Pkmyt1 antikoerper, pkmyt1.S antikoerper

Hintergrund: Pkmyt1 acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development (By similarity).

Molekulargewicht: 54053

Gen-ID: 268930

NCBI Accession: NP_075545

UniProt: Q9ESG9

Pathways: Mitotic G1-G1/S Phases, M Phase