SIRT6 Antikörper (C-Term)
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- Target Alle SIRT6 Antikörper anzeigen
- SIRT6 (Sirtuin 6 (SIRT6))
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Bindungsspezifität
- AA 276-305, C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SIRT6 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This SIRT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 276-305 amino acids from the C-terminal region of human SIRT6.
- Klon
- RB34031
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product SIRT6 Primärantikörper
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anti-Sirtuin 6 (SIRT6) (AA 1-334) antibody
SIRT6 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (AA 141-250) antibodySIRT6 Reaktivität: Human WB, ELISA, IHC, ICC, FACS Wirt: Maus Monoclonal 2G1H1 unconjugated
anti-Sirtuin 6 (SIRT6) antibodySIRT6 Reaktivität: Human, Maus, Ratte, Affe WB, IP, IF Wirt: Maus Monoclonal 6C9-D10-D3 unconjugated
anti-Sirtuin 6 (SIRT6) (AA 290-319), (C-Term) antibodySIRT6 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB2109 unconjugated
anti-Sirtuin 6 (SIRT6) (N-Term) antibodySIRT6 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schwein, Meerschweinchen, Pferd WB Wirt: Kaninchen Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (Middle Region) antibodySIRT6 Reaktivität: Human, Ratte, Hund, Rind (Kuh) WB, IP, ChIP Wirt: Kaninchen Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (AA 35-274) antibodySIRT6 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (AA 56-105) antibodySIRT6 Reaktivität: Human, Maus, Hund, Affe, Schwein, Fledermaus, Hamster WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Sirtuin 6 (SIRT6) (AA 141-250) antibodySIRT6 Reaktivität: Human ELISA Wirt: Maus Monoclonal 1D8 unconjugated
anti-Sirtuin 6 (SIRT6) (C-Term) antibodySIRT6 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB: 1:1000. IHC-P: 1:10~50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- SIRT6 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- Haltbarkeit
- 6 months
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- Target
- SIRT6 (Sirtuin 6 (SIRT6))
- Andere Bezeichnung
- SIRT6 (SIRT6 Produkte)
- Synonyme
- 2810449N18Rik antikoerper, AI043036 antikoerper, Sir2l6 antikoerper, SIR2L6 antikoerper, zgc:86729 antikoerper, sirtuin 6 antikoerper, sirtuin 6 S homeolog antikoerper, Sirt6 antikoerper, SIRT6 antikoerper, sirt6.S antikoerper, sirt6 antikoerper
- Hintergrund
- NAD-dependent protein deacetylase. Has deacetylase activity towards 'Lys-9' and 'Lys-56' of histone H3. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates 'Lys-9' of histone H3 at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Deacetylation of nucleosomes interferes with RELA binding to target DNA. May be required for the association of WRN with telomeres during S-phase and for normal telomere maintenance. Required for genomic stability. Required for normal IGF1 serum levels and normal glucose homeostasis. Modulates cellular senescence and apoptosis. Regulates the production of TNF protein (By similarity).
- Molekulargewicht
- 39119
- Gen-ID
- 51548
- NCBI Accession
- NP_001180214, NP_057623
- UniProt
- Q8N6T7
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