PRSS2 Antikörper

Produktnummer ABIN6571458

Produktdetails anti-PRSS2 Antikörper

Target: PRSS2 (Protease, serine, 2 (Trypsin 2) (PRSS2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRSS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human PRSS2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PRSS2

Target: PRSS2 (Protease, serine, 2 (Trypsin 2) (PRSS2))

Andere Bezeichnung: PRSS2 (PRSS2 Produkte)

Synonyme: Dvir\\GJ21501 antikoerper, Dvtry-2 antikoerper, GJ21501 antikoerper, Try2 antikoerper, dvir_GLEANR_6854 antikoerper, TRY8 antikoerper, TRYP antikoerper, Ta antikoerper, Tesp4 antikoerper, Ptryss2 antikoerper, TRY2 antikoerper, TRYP2 antikoerper, trypsin-2 antikoerper, Trypsin-2 antikoerper, protease, serine 2 antikoerper, protease, serine, 2 antikoerper, trypsin II antikoerper, CpipJ_CPIJ000771 antikoerper, CpipJ_CPIJ020109 antikoerper, Dvir\Try2 antikoerper, Prss2 antikoerper, PRSS2 antikoerper, trp-ii antikoerper

Hintergrund:

Synonyms: Anionic trypsinogen,EC 3.4.21.4,MGC111183,MGC120174,Protease serine 2 preproprotein ,Protease, serine, 2 (trypsin 2),Protease, serine, 2,Protease, serine, 2, preproprotein ,Prss2,Serine protease 2,TRY2,TRY2,TRY8,TRYP2,Trypsin 2,Trypsin II,Trypsin-2,Trypsinogen 2

Background: This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.

Molekulargewicht:

Observed_MW: 26kDa

Calculated_MW: 26kDa

Gen-ID: 5645

UniProt: P07478