PRSS2 Antikörper

Produktnummer ABIN7269580

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch PRSS2 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PRSS2 Antikörper (ABIN7269580)

Target: PRSS2 (Protease, serine, 2 (Trypsin 2) (PRSS2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser PRSS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-PRSS2 Antikörper

Verwendungszweck: PRSS2 Rabbit mAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human PRSS2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PRSS2

Target: PRSS2 (Protease, serine, 2 (Trypsin 2) (PRSS2))

Andere Bezeichnung: PRSS2

Hintergrund: This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.,PRSS2, TRY2, TRY8, TRYP2, trypsin-2,Cell Biology & Developmental Biology,Ubiquitin,PRSS2

Molekulargewicht: 30kDa

Gen-ID: 5645

UniProt: P07478