POLD2 Antikörper

Produktnummer ABIN5968284

Produktdetails anti-POLD2 Antikörper

Target: POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human POLD2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu POLD2

Target: POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))

Andere Bezeichnung: POLD2 (POLD2 Produkte)

Synonyme: 50kDa antikoerper, p50 antikoerper, po1D2 antikoerper, cdc1 antikoerper, si:dz150f13.3 antikoerper, zgc:55633 antikoerper, zgc:77043 antikoerper, DNA polymerase delta 2, accessory subunit antikoerper, polymerase (DNA directed), delta 2, regulatory subunit antikoerper, polymerase (DNA directed), delta 2, accessory subunit L homeolog antikoerper, POLD2 antikoerper, Pold2 antikoerper, pold2.L antikoerper, pold2 antikoerper

Hintergrund:

Synonyms: DNA polymerase delta subunit 2,DNA polymerase delta subunit p50,DNA polymerase subunit delta 2,DNA polymerase subunit delta p50,DPOD2,POLD 2,pold2

Background: This gene encodes the 50-  kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein is required for the stimulation of DNA polymerase delta activity by the processivity cofactor proliferating cell nuclear antigen (PCNA). Expression of this gene may be a marker for ovarian carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.

Molekulargewicht:

Observed_MW: 50kDa

Calculated_MW: 51kDa

Gen-ID: 5425

UniProt: P49005

Pathways: Telomere Maintenance, DNA Reparatur, DNA Replication, Synthesis of DNA