MUS81 Antikörper
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- Target Alle MUS81 Antikörper anzeigen
- MUS81 (MUS81 Endonuclease Homolog (MUS81))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MUS81 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein of human MUS81 (NP_079404.3).
- Isotyp
- IgG
- Top Product
- Discover our top product MUS81 Primärantikörper
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- Applikationshinweise
- IHC 1:50-1:100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- MUS81 (MUS81 Endonuclease Homolog (MUS81))
- Andere Bezeichnung
- MUS81 (MUS81 Produkte)
- Synonyme
- CG3026 antikoerper, Dmel\\CG3026 antikoerper, EG:BACR7A4.16 antikoerper, MUS81 antikoerper, GB15332 antikoerper, ARABIDOPSIS THALIANA MMS AND UV SENSITIVE 81 antikoerper, ATMUS81 antikoerper, F6I18.220 antikoerper, F6I18_220 antikoerper, MMS AND UV SENSITIVE 81 antikoerper, SLX3 antikoerper, slx3 antikoerper, 1200008A18Rik antikoerper, AI182501 antikoerper, AW045863 antikoerper, wu:fc26g01 antikoerper, zgc:66489 antikoerper, zgc:91801 antikoerper, CG3026 gene product from transcript CG3026-RA antikoerper, MUS81 structure-specific endonuclease subunit antikoerper, crossover junction endonuclease MUS81 antikoerper, Restriction endonuclease, type II-like superfamily protein antikoerper, Mus81p antikoerper, Holliday junction resolvase subunit Mus81 antikoerper, MUS81 protein antikoerper, hypothetical protein antikoerper, mus81 antikoerper, MUS81 antikoerper, LOC725951 antikoerper, Mus81 antikoerper, CAALFM_C600540WA antikoerper
- Hintergrund
- This gene encodes a structure-specific endonuclease which belongs to the XPF/MUS81 endonuclease family and plays a critical role in the resolution of recombination intermediates during DNA repair after inter-strand cross-links, replication fork collapse, and DNA double-strand breaks. The encoded protein associates with one of two closely related essential meiotic endonuclease proteins (EME1 or EME2) to form a complex that processes DNA secondary structures. It contains an N-terminal DEAH helicase domain, an excision repair cross complementation group 4 (ERCC4) endonuclease domain, and two tandem C-terminal helix-hairpin-helix domains. Mice with a homozygous knockout of the orthologous gene have significant meiotic defects including the failure to repair a subset of DNA double strand breaks.
- Molekulargewicht
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Observed_MW: 60kDa
Calculated_MW: 61kDa
- Gen-ID
- 80198
- UniProt
- Q96NY9
- Pathways
- DNA Reparatur
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