Caspase 4 Antikörper
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- Target Alle Caspase 4 (CASP4) Antikörper anzeigen
- Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Caspase 4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant protein of mouse CASP4
- Isotyp
- IgG
- Top Product
- Discover our top product CASP4 Primärantikörper
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- Applikationshinweise
- WB 1:500 - 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))
- Andere Bezeichnung
- CASP4 (CASP4 Produkte)
- Synonyme
- ICE(rel)II antikoerper, ICEREL-II antikoerper, ICH-2 antikoerper, Mih1/TX antikoerper, TX antikoerper, Casp11 antikoerper, CASP13 antikoerper, CASP1 antikoerper, CASP4 antikoerper, Caspl antikoerper, ich-3 antikoerper, Casp4 antikoerper, caspase 4 antikoerper, caspase 4, apoptosis-related cysteine peptidase antikoerper, caspase-4 antikoerper, CASP4 antikoerper, Casp4 antikoerper, LOC100731032 antikoerper
- Hintergrund
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Synonyms: Apoptotic cysteine protease Mih1/TX,CASP-4,CASP4,CASP4,Caspase 4 apoptosis related cysteine peptidase,Caspase-4 subunit 2,Caspase4,ICE(rel)-II,ICE(rel)II,ICEREL II,ICH2,Mih1/TX,Protease ICH-2,Protease TX,TX
Background: This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.
- Molekulargewicht
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Observed_MW: 43-48kDa
Calculated_MW: 13kDa/18kDa/30kDa/36kDa/43kDa
- Gen-ID
- 12363
- UniProt
- P70343
- Pathways
- Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity
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