Kallikrein 7 Antikörper

Produktnummer ABIN5963671

Produktdetails anti-Kallikrein 7 Antikörper

Target: Kallikrein 7 (KLK7)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Kallikrein 7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human KLK7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Kallikrein 7

Target: Kallikrein 7 (KLK7)

Andere Bezeichnung: KLK7 (KLK7 Produkte)

Synonyme: Prss6 antikoerper, SCCE antikoerper, PRSS6 antikoerper, hK7 antikoerper, kallikrein related-peptidase 7 (chymotryptic, stratum corneum) antikoerper, kallikrein-related peptidase 7 antikoerper, kallikrein related peptidase 7 antikoerper, Klk7 antikoerper, KLK7 antikoerper

Hintergrund:

Synonyms: Chymotryptic stratum corneum,hK 7,hK7,hSCCE,Kallikrein 7 (chymotryptic stratum corneum),Kallikrein related peptidase 7,Kallikrein-7,Kallikrein7,KLK 7,Klk7,KLK7,Protease serine 6,PRSS 6,PRSS6,SCCE,Serine protease 6,Signal protein,Stratum corneum chymotryptic enzyme

Background: This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19.

Molekulargewicht:

Observed_MW: 30kDa

Calculated_MW: 19kDa/27kDa

Gen-ID: 5650

UniProt: P49862

Pathways: Komplementsystem