DYNC2LI1 Antikörper

Produktnummer ABIN6569748

Produktdetails anti-DYNC2LI1 Antikörper

Target: DYNC2LI1 (Dynein, Cytoplasmic 2, Light Intermediate Chain 1 (DYNC2LI1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DYNC2LI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human DYNC2LI1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DYNC2LI1

Target: DYNC2LI1 (Dynein, Cytoplasmic 2, Light Intermediate Chain 1 (DYNC2LI1))

Andere Bezeichnung: DYNC2LI1 (DYNC2LI1 Produkte)

Synonyme: DYNC2LI1 antikoerper, 4933404O11Rik antikoerper, CGI-60 antikoerper, D2lic antikoerper, LIC3 antikoerper, mD2LIC antikoerper, D2LIC antikoerper, dynein cytoplasmic 2 light intermediate chain 1 antikoerper, DYNC2LI1 antikoerper, Dync2li1 antikoerper

Hintergrund:

Synonyms: CGI-60,Cytoplasmic dynein 2 light intermediate chain 1,D2LIC,DC2L1,DYNC2LI1,Dynein 2 light intermediate chain,Dynein, cytoplasmic 2, light intermediate chain 1,LIC3

Background: This gene encodes a protein that is a component of the dynein-2 microtubule motor protein complex that plays a role in the retrograde transport of cargo in primary cilia via the intraflagellar transport system. This gene is ubiquitously expressed and its protein, which localizes to the axoneme and Golgi apparatus, interacts directly with the cytoplasmic dynein 2 heavy chain 1 protein to form part of the multi-protein dynein-2 complex. Mutations in this gene produce defects in the dynein-2 complex which result in several types of ciliopathy including short-rib thoracic dysplasia 15 with polydactyly (SRTD15). Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molekulargewicht:

Observed_MW: 38kDa

Calculated_MW: 15kDa/22kDa/37kDa/39kDa

Gen-ID: 51626

UniProt: Q8TCX1

Pathways: Hedgehog Signalweg