FANCI Antikörper

Produktnummer ABIN6569525

Produktdetails anti-FANCI Antikörper

Target: FANCI (Fanconi Anemia Complementation Group I (FANCI))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FANCI Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human FANCI

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu FANCI

Target: FANCI (Fanconi Anemia Complementation Group I (FANCI))

Andere Bezeichnung: FANCI (FANCI Produkte)

Synonyme: KIAA1794 antikoerper, Fanconi anemia complementation group I antikoerper, Fanconi anemia, complementation group I antikoerper, FANCI antikoerper, Fanci antikoerper

Hintergrund:

Synonyms: FANCI,FANCI gene,FANCI,Fanconi anemia group I protein,Fanconi anemia, complementation group I,FLJ10719,FLJ14658,KIAA1794,Protein FACI,Protein FANCI

Background: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group I. Alternative splicing results in two transcript variants encoding different isoforms.

Molekulargewicht:

Observed_MW: 170kDa

Calculated_MW: 27kDa/142kDa/149kDa

Gen-ID: 55215

UniProt: Q9NVI1

Pathways: DNA Reparatur