CNTF Receptor alpha Antikörper

Produktnummer ABIN6569324

Produktdetails anti-CNTF Receptor alpha Antikörper

Target: CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CNTF Receptor alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human CNTFR

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:400 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CNTF Receptor alpha

Target: CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))

Andere Bezeichnung: CNTFR (CNTFR Produkte)

Synonyme: CNTFR-alpha antikoerper, CNTFRALPHA antikoerper, Cntfralpha antikoerper, cb549 antikoerper, fj33e02 antikoerper, sb:cb549 antikoerper, wu:fj33e02 antikoerper, si:bz76a6.1 antikoerper, si:dz248f2.1 antikoerper, si:rp71-76a6.1 antikoerper, ciliary neurotrophic factor receptor antikoerper, ciliary neurotrophic factor receptor L homeolog antikoerper, CNTFR antikoerper, cntfr.L antikoerper, Cntfr antikoerper, cntfr antikoerper

Hintergrund:

Synonyms: Ciliary neurotrophic factor receptor alpha ,Ciliary neurotrophic factor receptor,Ciliary neurotrophic factor receptor subunit alpha,CNTF receptor subunit alpha,CNTFR Alpha,CNTFR,CNTFR-alpha,CNTFR

Background: This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.

Molekulargewicht:

Observed_MW: 41kDa

Calculated_MW: 40kDa

Gen-ID: 1271

UniProt: P26992

Pathways: JAK-STAT Signalweg, Feeding Behaviour