OPTN Antikörper

Produktnummer ABIN5963871

Produktdetails anti-OPTN Antikörper

Target: OPTN (Optineurin (OPTN))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OPTN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human OPTN

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu OPTN

Target: OPTN (Optineurin (OPTN))

Andere Bezeichnung: OPTN (OPTN Produkte)

Synonyme: nrp antikoerper, fip2 antikoerper, hip7 antikoerper, hypl antikoerper, glc1e antikoerper, tfiiia-intp antikoerper, ALS12 antikoerper, FIP2 antikoerper, GLC1E antikoerper, HIP7 antikoerper, HYPL antikoerper, NRP antikoerper, TFIIIA-INTP antikoerper, Fip2 antikoerper, 4930441O07Rik antikoerper, fj52f04 antikoerper, si:ch211-240l19.3 antikoerper, wu:fj52f04 antikoerper, zgc:66386 antikoerper, zgc:77868 antikoerper, optineurin antikoerper, optineurin L homeolog antikoerper, OPTN antikoerper, optn antikoerper, Optn antikoerper, optn.L antikoerper

Hintergrund:

Synonyms: 14.7K interacting protein,Ag9 C5,ALS12,E3 14.7K interacting protein,E3-14.7K-interacting protein,FIP 2,FIP-2,FIP2,Glaucoma 1 open angle E (adult onset),Glaucoma 1 open angle E,GLC1E,HIP 7,HIP-7,HIP7,Huntingtin interacting protein 7,Huntingtin interacting protein HYPL,Huntingtin interacting protein L,Huntingtin yeast partner L,Huntingtin-interacting protein 7,Huntingtin-interacting protein L,HYPL,Injury inducible protein I 55,NEMO related protein,NEMO-related protein,NRP,Optic neuropathy inducing protein,Optic neuropathy-inducing protein,Optineurin,OPTN,OPTN,TFIIIA IntP,TFIIIA-IntP,Transcription factor IIIA interacting protein,Transcription factor IIIA-interacting protein,Tumor necrosis factor alpha inducible cellular protein containing leucine zipper domains

Background: This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.

Molekulargewicht:

Observed_MW: 78kDa

Calculated_MW: 59kDa/65kDa

Gen-ID: 10133

UniProt: Q96CV9

Pathways: M Phase