IBTK Antikörper

Produktnummer ABIN6568506

Produktdetails anti-IBTK Antikörper

Target: IBTK (Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IBTK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human IBTK

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu IBTK

Target: IBTK (Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK))

Andere Bezeichnung: IBTK (IBTK Produkte)

Synonyme: IBTK antikoerper, fi40c08 antikoerper, wu:fi40c08 antikoerper, DKFZp468J085 antikoerper, BTBD26 antikoerper, BTKI antikoerper, RP1-93K22.1 antikoerper, 5430411K16Rik antikoerper, AA409502 antikoerper, mKIAA1417 antikoerper, inhibitor of Bruton tyrosine kinase antikoerper, inhibitor of Bruton agammaglobulinemia tyrosine kinase antikoerper, inhibitor of Bruton tyrosine kinase L homeolog antikoerper, IBTK antikoerper, ibtk antikoerper, Ibtk antikoerper, ibtk.L antikoerper

Hintergrund:

Synonyms: BTKI,IBtk,IBTK,inhibitor of Bruton agammaglobulinemia tyrosine kinase,Inhibitor of Bruton tyrosine kinase

Background: Bruton tyrosine kinase (BTK) is a protein tyrosine kinase that is expressed in B cells, macrophages, and neutrophils. The protein encoded by this gene binds to BTK and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. This gene has a pseudogene on chromosome 18. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Molekulargewicht:

Observed_MW: 167kDa

Calculated_MW: 26kDa/133kDa/150kDa

Gen-ID: 25998

UniProt: Q9P2D0