IBTK Antikörper (AA 900-1200)
Kurzübersicht für IBTK Antikörper (AA 900-1200) (ABIN7267871)
Target
Alle IBTK Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 900-1200
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Verwendungszweck
- IBTK Rabbit pAb
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Sequenz
- GLNMAALLEA RSLDVLSDGV LKDLSEFYRK MIPAMDRRVI TPYQDGPDIS YLEVEDGDIF LKEEINMEQN HSETMFKKAK TKAKKKPRKR SDSSGGYNLS DIIQSPSSTG LLKSGKTNSV ESLPELLTSD SEGSYAGVGS PRDLQSPDFT TGFHSDKIEA KVKPYVNGTS PVYSREDLKP WEKSPILKIS APQPIPSNRI DTTSSASWVA GSFSPVSPPV VDLRTIMEIE ESRQKCGATP KSHLGKTVSH GVKLSQKQRK MIALTTKENN SGMNSMETVL FTPSKAPKPV NAWASSLHSV S
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Kreuzreaktivität
- Human
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 900-1200 of human IBTK (NP_056340.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- IBTK (Inhibitor of Bruton Agammaglobulinemia Tyrosine Kinase (IBTK))
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Andere Bezeichnung
- IBTK
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Hintergrund
- Bruton tyrosine kinase (BTK) is a protein tyrosine kinase that is expressed in B cells, macrophages, and neutrophils. The protein encoded by this gene binds to BTK and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. This gene has a pseudogene on chromosome 18. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,IBTK,BTBD26,BTKI,Signal Transduction,Kinase,IBTK
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Molekulargewicht
- 26kDa/133kDa/150kDa
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Gen-ID
- 25998
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UniProt
- Q9P2D0
Target
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