UIMC1 Antikörper

Produktnummer ABIN6568375

Produktdetails anti-UIMC1 Antikörper

Target: UIMC1 (Ubiquitin Interaction Motif Containing 1 (UIMC1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UIMC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human UIMC1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu UIMC1

Target: UIMC1 (Ubiquitin Interaction Motif Containing 1 (UIMC1))

Andere Bezeichnung: UIMC1 (UIMC1 Produkte)

Synonyme: UIMC1 antikoerper, RAP80 antikoerper, X2HRIP110 antikoerper, 9430016E08Rik antikoerper, D330018D10Rik antikoerper, D630032M02Rik antikoerper, RIP110 antikoerper, Rxrip110 antikoerper, RGD1307009 antikoerper, ubiquitin interaction motif containing 1 antikoerper, UIMC1 antikoerper, Uimc1 antikoerper

Hintergrund:

Synonyms: BRCA1-A complex subunit RAP80,Nuclear zinc finger protein RAP80,OTTHUMP00000161441,OTTHUMP00000223372,OTTHUMP00000223374,RAP80,Receptor associated protein 80,Receptor-associated protein 80,Retinoid X receptor interacting protein 110,Retinoid x receptor interacting protein,Retinoid X receptor-interacting protein 110,RIP110,Rxrip110,Ubiquitin interaction motif containing 1,Ubiquitin interaction motif containing protein 1,Ubiquitin interaction motif-containing protein 1,UIMC1,UIMC1,X2HRIP110

Background: This gene encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants.

Molekulargewicht:

Observed_MW: 90kDa

Calculated_MW: 17kDa/38kDa/61kDa/70kDa/79kDa

Gen-ID: 51720

UniProt: Q96RL1

Pathways: DNA Reparatur, Nuclear Hormone Receptor Binding, Positive Regulation of Response to DNA Damage Stimulus