DOC2A Antikörper (Double C2-Like Domains, alpha) (AA 277-306)

Details for Product anti-DOC2A Antibody No. ABIN656766, Anbieter: Anmelden zum Anzeigen
Antigen
  • DOC2A
  • doc2-A
  • Doc2
  • double C2 domain alpha
  • double C2-like domains, alpha
  • double C2, alpha
  • DOC2A
  • doc2a
  • Doc2a
Epitop
AA 277-306, Center
10
10
9
9
4
4
4
2
2
1
1
1
1
Reaktivität
Human
40
6
4
4
4
2
2
2
1
1
1
1
Wirt
Kaninchen
27
8
5
2
Klonalität (Klon)
Polyklonal ()
Konjugat
Dieser DOC2A Antikörper ist unkonjugiert
2
2
2
2
2
2
Applikation
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
31
27
17
16
5
2
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen This DOC2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-306 AA from the Central region of human DOC2A.
Klon RB32573
Isotyp Ig Fraction
Spezifität This DOC2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 284-314 amino acids from the Central region of human DOC2A.
Homologie Mouse (Murine),Rat (Rattus)
Reinigung This antibody is purified through a protein A column, followed by peptide affinity purification.
Andere Bezeichnung DOC2A (DOC2A Antibody Abstract)
Hintergrund There are at least two protein isoforms of the Double C2 protein, namely alpha (DOC2A) and beta (DOC2B), which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes, these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2A is mainly expressed in brain and is suggested to be involved in Ca(2+)-dependent neurotransmitter release.
Synonyms: Double C2-like domain-containing protein alpha,DOC2A,
Molekulargewicht 43959 DA
Gen-ID 8448
NCBI Accession NP_003577
UniProt Q14183
Forschungsgebiet Cell Structure, Neurology
Pathways Synaptic Vesicle Exocytosis
Applikationshinweise FACS = 1:10-50, WB = 1:1000, IHC (p) = 1:10-50
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung DOC2A Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Haltbarkeit 6 months
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Double C2-Like Domains, alpha (DOC2A) (AA 277-306), (Center) antibody (ABIN656766) DOC2A Antibody (Center) (ABIN656766) immunohistochemistry analysis in formalin fixed ...
Allgemeine Veröffentlichungen Shimada, Miyagawa, Kawashima, Tanaka, Honda, Honda, Tokunaga: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." in: Human genetics, Vol. 128, Issue 4, pp. 433-41, 2010 (PubMed).

Glessner, Reilly, Kim, Takahashi, Albano, Hou, Bradfield, Zhang, Sleiman, Flory, Imielinski, Frackelton, Chiavacci, Thomas, Garris, Otieno, Davidson, Weiser, Reichenberg, Davis, Friedman, Cappola, Margulies, Rader, Grant, Buxbaum, Gur, Hakonarson: "Strong synaptic transmission impact by copy number variations in schizophrenia." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 23, pp. 10584-9, 2010 (PubMed).

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