DOC2A Antikörper (AA 652-749)

Produktnummer ABIN5542714

Produktdetails anti-DOC2A Antikörper

Target: DOC2A (Double C2-Like Domains, alpha (DOC2A))

Bindungsspezifität: AA 652-749

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DOC2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human DOC2 (AA: 652-749) expressed in E. coli.

Klon: 2H7C4

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: , ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu DOC2A

Target: DOC2A (Double C2-Like Domains, alpha (DOC2A))

Andere Bezeichnung: DOC2 (DOC2A Produkte)

Synonyme: DOC2A antikoerper, doc2-A antikoerper, Doc2 antikoerper, double C2 domain alpha antikoerper, double C2-like domains, alpha antikoerper, double C2, alpha antikoerper, DOC2A antikoerper, doc2a antikoerper, Doc2a antikoerper

Hintergrund:

Description: This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,

Aliases: DAB2, DOC-2

Molekulargewicht: 82.4 kDa

Gen-ID: 1601

HGNC: 5899

Pathways: Synaptic Vesicle Exocytosis