Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 13 (PSMD13) Antikörper

Details zu Produkt Nr. ABIN6567507
Target
Reaktivität
Human, Maus, Ratte
39
12
11
1
1
1
1
1
Wirt
Kaninchen
38
2
Klonalität
Polyklonal
Konjugat
Unkonjugiert
3
2
2
2
2
2
1
1
1
1
1
1
Applikation
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
35
23
19
17
4
3
1
1
1
1
1
Optionen
Immunogen Recombinant protein of human PSMD13
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung PSMD13 (PSMD13 Antibody Abstract)
Hintergrund

Synonyms: 26S proteasome non ATPase regulatory subunit 13,26S proteasome non-ATPase regulatory subunit 13,26S proteasome regulatory subunit p40.5,26S proteasome regulatory subunit RPN9,26S proteasome regulatory subunit S11,26S proteasome subunit p40.5,HSPC027,P40.5,Proteasome (prosome, macropain) 26S subunit, non ATPase, 13,Proteasome 26S subunit, non-ATPase 13,PSD13,psmD13,Rpn9,S11

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described.

Molekulargewicht

Observed_MW: 45kDa

Calculated_MW: 42kDa

Gen-ID 5719
UniProt Q9UNM6
Pathways Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
Applikations-hinweise WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Konzentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C. Avoid freeze / thaw cycles.
Bilder
Image no. 1 for anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 13 (PSMD13) antibody (ABIN6567507) Immunohistochemistry of paraffin-embedded human esophagus using PSMD13 antibody.
Image no. 2 for anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 13 (PSMD13) antibody (ABIN6567507) Western blot analysis of extracts of various cell lines, using PSMD13 Antibody.
Image no. 3 for anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 13 (PSMD13) antibody (ABIN6567507) Immunofluorescence analysis of U2OS cells using PSMD13 antibody.
Image no. 4 for anti-Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 13 (PSMD13) antibody (ABIN6567507) Immunohistochemistry of paraffin-embedded rat brain using PSMD13 antibody.