PKLR Antikörper

Produktnummer ABIN5963923

Produktdetails anti-PKLR Antikörper

Target: PKLR (Pyruvate Kinase, Liver and RBC (PKLR))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKLR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human PKLR

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PKLR

Target: PKLR (Pyruvate Kinase, Liver and RBC (PKLR))

Andere Bezeichnung: PKLR (PKLR Produkte)

Synonyme: PK1 antikoerper, PKL antikoerper, PKR antikoerper, PKRL antikoerper, RPK antikoerper, Pklg antikoerper, wu:fd15e01 antikoerper, wu:fi37e08 antikoerper, pk1 antikoerper, PKLR antikoerper, Pk-1 antikoerper, Pk1 antikoerper, R-PK antikoerper, pklr antikoerper, pyruvate kinase L/R antikoerper, pyruvate kinase, liver and RBC antikoerper, pyruvate kinase, liver and RBC L homeolog antikoerper, pyruvate kinase liver and red blood cell antikoerper, pyruvate kinase PKLR-like antikoerper, PKLR antikoerper, Pklr antikoerper, pklr antikoerper, pklr.L antikoerper, LOC100621940 antikoerper

Hintergrund:

Synonyms: EC 2.7.1.40,KPYR,L-PK,Pk-1,PK1 ,PKL ,Pklg,Pklr,PKR,PKRL,Pyruvate kinase 1,Pyruvate kinase isozymes R/L,Pyruvate kinase liver and blood cell,Pyruvate kinase liver and RBC,Pyruvate kinase liver and red blood cell,Pyruvate kinase liver type,Pyruvate kinase type L,Pyruvate kinase, red cell type,R type/L type pyruvate kinase,R-PK,R-type/L-type pyruvate kinase,Red cell/liver pyruvate kinase,RPK

Background: The protein encoded by this gene is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht:

Observed_MW: 62kDa

Calculated_MW: 58kDa/61kDa

Gen-ID: 5313

UniProt: P30613

Pathways: Ribonucleoside Biosynthetic Process