Nibrin Antikörper
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- Target Alle Nibrin (NBN) Antikörper anzeigen
- Nibrin (NBN)
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Nibrin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- Affinity purification
- Immunogen
- A synthetic peptide of human NBN
- Isotyp
- IgG
- Top Product
- Discover our top product NBN Primärantikörper
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- Applikationshinweise
- WB 1:500 - 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Nibrin (NBN)
- Andere Bezeichnung
- NBN (NBN Produkte)
- Synonyme
- NBN antikoerper, AT-V1 antikoerper, AT-V2 antikoerper, ATV antikoerper, NBS antikoerper, NBS1 antikoerper, P95 antikoerper, Nbs1 antikoerper, im:6911679 antikoerper, zgc:194152 antikoerper, nibrin antikoerper, NBN antikoerper, nbn antikoerper, Nbn antikoerper
- Hintergrund
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Synonyms: AT V1,AT V2,ATV,Cell cycle regulatory protein p95,FLJ10155,MGC87362,Nbn,NBN,NBS 1,NBS,NBS1,Nibrin,Nijmegen breakage syndrome 1 (nibrin),Nijmegen breakage syndrome,Nijmegen breakage syndrome protein 1,p95,p95 protein of the MRE11/RAD50 complex
Background: Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.
- Molekulargewicht
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Observed_MW: 95kDa
Calculated_MW: 84kDa
- Gen-ID
- 4683
- UniProt
- O60934
- Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
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