Cadherin 5 Antikörper

Produktnummer ABIN5964584

Produktdetails anti-Cadherin 5 Antikörper

Target: Cadherin 5 (CDH5)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cadherin 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human CDH5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Cadherin 5

Target: Cadherin 5 (CDH5)

Andere Bezeichnung: VE-Cadherin (CDH5 Produkte)

Synonyme: 7B4 antikoerper, AA408225 antikoerper, Cd144 antikoerper, VE-Cad antikoerper, VECD antikoerper, VEcad antikoerper, Vec antikoerper, wu:fc88a07 antikoerper, CD144 antikoerper, cadherin-5 antikoerper, cadherin 5 antikoerper, CDH5 antikoerper, Cdh5 antikoerper, cdh5 antikoerper

Hintergrund:

Synonyms: 7B 4,7B4,7B4 antigen,CADH5,Cadherin 5,Cadherin 5 type 2,Cadherin 5,type 2 (vascular endothelium),Cadherin 5,type 2,VE cadherin (vascular epithelium),cadherin,vascular endothelial,cadherin,vascular endothelial,1,Cadherin-5,Cadherin5,CD 144,CD144,CD144 antigen,CDH 5,CDH5,CDH5 protein,Endothelial specific cadherin,FLJ17376,OTTHUMP00000174777,Vascular endothelial cadherin,Vascular epithelium cadherin,VE Cad,VE-cadherin,VEC

Background: This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.

Molekulargewicht:

Observed_MW: 120kDa

Calculated_MW: 74kDa/87kDa

Gen-ID: 1003

UniProt: P33151

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2