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Cadherin 5 Antikörper (C-Term)

Name: Cadherin 5 Antikörper (C-Term)
SKU: ABIN6265962
Price: 698.46 EUR
Availability: InStock

CDH5 Reaktivität: Human, Maus WB, IHC, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated

Western blot analysis of VE-Cadherin expression in Jurkat whole cell lysates,The lane on the left is treated with the antigen-specific peptide. (Cadherin 5 Antikörper (C-Term))

IF/ICC

ABIN6269219 at 1/100 staining Human liver cancer tissue by IHC-P. (Cadherin 5 Antikörper (C-Term))

IHC

3 Abbildungen

(2 Referenzen)

Produktnummer ABIN6265962

Datenblatt (PDF)

Target Alle Cadherin 5 (CDH5) Antikörper anzeigen

Cadherin 5 (CDH5)
Bindungsspezifität
16

12

7

6

4

4

3

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
Reaktivität
105

68

43

3

2

1

1

1

1

1

1
Human, Maus
Wirt
87

33

9

1
Kaninchen
Passende Sekundärantikörper
Klonalität
84

46
Polyklonal
Konjugat
72

7

7

6

4

4

4

3

3

3

3

3

2

1

1

1

1

1

1

1

1

1
Dieser Cadherin 5 Antikörper ist unkonjugiert
Applikation
88

43

38

37

25

15

15

14

14

13

12

5

5

4

4

4

3

3

2

2

2

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Spezifität

VE-Cadherin Antibody detects endogenous levels of total VE-Cadherin.

Homologie

Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken

Aufreinigung

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen

A synthesized peptide derived from human VE-Cadherin, corresponding to a region within C-terminal amino acids.

Isotyp

IgG

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Applikationshinweise

WB 1:500-1:2000, IHC 1:200, IF/ICC 1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit

12 months
Meng, Chen, Lei, Han, Zhong, Wang, Liu, Gao, Zhang, Tan, Liu, Zhou, Sun, Yang: "Hsp90β promotes aggressive vasculogenic mimicry via epithelial-mesenchymal transition in hepatocellular carcinoma." in: Oncogene, (2018) (PubMed).

Lv, Phuong, Jin, Li, Xu: "Protection by simvastatin on hyperglycemia-induced endothelial dysfunction through inhibiting NLRP3 inflammasomes." in: Oncotarget, Vol. 8, Issue 53, pp. 91291-91305, (2017) (PubMed).
Target

Cadherin 5 (CDH5)

Andere Bezeichnung

CDH5 (CDH5 Produkte)

Synonyme

7B4 antikoerper, AA408225 antikoerper, Cd144 antikoerper, VE-Cad antikoerper, VECD antikoerper, VEcad antikoerper, Vec antikoerper, wu:fc88a07 antikoerper, CD144 antikoerper, cadherin-5 antikoerper, cadherin 5 antikoerper, CDH5 antikoerper, Cdh5 antikoerper, cdh5 antikoerper

Hintergrund

Description: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for the localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction.
Gene: CDH5

Molekulargewicht

120kDa

Gen-ID

1003

UniProt

P33151

Pathways

Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2