CLEC12A Antikörper (C-Type Lectin Domain Family 12, Member A) (AA 178-206)

Details for Product anti-CLEC12A Antibody No. ABIN653995, Anbieter: Anmelden zum Anzeigen
Antigen
  • MGC179455
  • CLL-1
  • CLL1
  • DCAL-2
  • MICL
  • D230024O04
  • KLRL1
  • Micl
  • C-type lectin domain family 12 member A
  • C-type lectin domain family 12, member a
  • C-type lectin domain family 12, member A
  • CLEC12A
  • Clec12a
Epitop
AA 178-206, Center
16
7
7
6
4
2
2
1
1
1
1
1
Reaktivität
Human
65
24
20
Wirt
Kaninchen
49
11
6
1
Klonalität (Klon)
Polyklonal ()
Konjugat
Dieser CLEC12A Antikörper ist unkonjugiert
3
3
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
39
23
13
13
8
4
3
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen This CLEC12A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 178-206 AA from the Central region of human CLEC12A.
Klon RB27646
Isotyp Ig Fraction
Reinigung This antibody is purified through a protein A column, followed by peptide affinity purification.
Plasmids, Primers & others Plasmide, Primers & weitere CLEC12A products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung CLEC12A (CLEC12A Antibody Abstract)
Hintergrund Function
Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.

Cellular Location
Cell membrane, Single-pass type II membrane protein. Note=Ligand binding leads to internalization

Tissue Location
Detected in normal myeloid cells and in acute myeloid leukemia cells. Detected in neutrophils, eosinophils, monocytes and dendritic cells. Detected in spleen macrophage-rich red pulp and in lymph node (at protein level). Detected in peripheral blood leukocytes, dendritic cells, bone marrow, monocytes, mononuclear leukocytes and macrophages

Synonyms: CLEC12A,CLL1, DCAL2, MICL
Molekulargewicht 30762 Da
Gen-ID 160364
NCBI Accession NP_963917, NP_612210
UniProt Q5QGZ9
Applikations-hinweise Suggested dilutions:
WB = 1:1000
Optimal working dilution should be determined by the investigator.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handhabung Avoid freeze-thaw cycles.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
Haltbarkeit 6 months
Bilder des Herstellers
Western Blotting (WB) image for anti-C-Type Lectin Domain Family 12, Member A (CLEC12A) (AA 178-206), (Center) antibody (ABIN653995) CLEC12A Antibody (Center) (ABIN653995) western blot analysis in ZR-75-1 cell line lys...
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