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CLEC12A Antikörper (AA 61-160)

CLEC12A Reaktivität: Human WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1713749
  • Target Alle CLEC12A Antikörper anzeigen
    CLEC12A (C-Type Lectin Domain Family 12, Member A (CLEC12A))
    Bindungsspezifität
    • 14
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 61-160
    Reaktivität
    • 44
    • 15
    • 11
    Human
    Wirt
    • 37
    • 6
    • 3
    • 1
    Kaninchen
    Klonalität
    • 37
    • 10
    Polyklonal
    Konjugat
    • 15
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CLEC12A Antikörper ist unkonjugiert
    Applikation
    • 31
    • 15
    • 12
    • 12
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Homologie
    Human,Mouse,Rat
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CLEC12A
    Isotyp
    IgG
    Top Product
    Discover our top product CLEC12A Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    CLEC12A (C-Type Lectin Domain Family 12, Member A (CLEC12A))
    Andere Bezeichnung
    CLEC12A (CLEC12A Produkte)
    Synonyme
    MGC179455 antikoerper, CLL-1 antikoerper, CLL1 antikoerper, DCAL-2 antikoerper, MICL antikoerper, D230024O04 antikoerper, KLRL1 antikoerper, Micl antikoerper, C-type lectin domain family 12 member A antikoerper, C-type lectin domain family 12, member a antikoerper, C-type lectin domain family 12, member A antikoerper, CLEC12A antikoerper, Clec12a antikoerper
    Hintergrund

    Synonyms: C-type lectin domain family 12 member A, C-type lectin-like molecule 1, CL12A_HUMAN, CLEC12A, CLL-1, DCAL-2, Dendritic cell-associated lectin 2, MICL, Myeloid inhibitory C-type lectin-like receptor.

    Background: The C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily consists of a variety of proteins that share a common protein fold and have diverse functions, including cell-cell signaling, cell adhesion, glycoprotein turnover and immune responses. CLEC-12A (C-type lectin domain family 12, member A), also known as CLL1, MICL, CLL-1 or DCAL-2, is a 275 amino acid single-pass type II membrane protein that contains one C-type lectin domain and belongs to the CTL/CTLD superfamily. Existing as multiple alternatively spliced isoforms that are expressed in neutrophils, eosinophils, monocytes and dendritic cells, CLEC-12A functions as a cell surface receptor that acts as a negative regulator of granulocyte and monocyte function and, via this activity, modulates signaling cascades. CLEC-12A is highly subject to post-translational glycosylation at its N-terminus and may also exist as a homodimer.

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