PIK3 gamma Antikörper
Kurzübersicht für PIK3 gamma Antikörper (ABIN652433)
Target
Alle PIK3 gamma (PIK3CG) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
Immunogen
- This PIK3CG antibody is generated from rabbits immunized with human PIK3CG Recombinant Protein.
-
Isotyp
- Ig Fraction
-
-
-
-
Applikationshinweise
- WB: 1:1000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
-
Haltbarkeit
- 6 months
-
-
- PIK3 gamma (PIK3CG) (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))
-
Andere Bezeichnung
- PIK3CG
-
Hintergrund
- PIK3CG belongs to the pi3/pi4-kinase family of proteins. It is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene for this protein is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias.
-
Molekulargewicht
- 126454
-
Gen-ID
- 5294
-
NCBI Accession
- NP_001269355, NP_001269356, NP_002640
-
UniProt
- P48736
-
Pathways
- PI3K-Akt Signalweg, RTK Signalweg, AMPK Signaling, TLR Signalweg, Inositol Metabolic Process, Hepatitis C, VEGF Signaling
Target
-