PIK3 gamma Antikörper (C-Term)

Produktnummer ABIN2855878

Produktdetails anti-PIK3 gamma Antikörper

Target: PIK3 gamma (PIK3CG) (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIK3 gamma Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Maus, Zebrafisch (Danio rerio), Xenopus tropicalis, Schwein, Huhn, Rhesusaffen

Kreuzreaktivität (Details): Mouse (100 %), Zebrafish (85 %), Xenopus Tropicalis (92 %), Pig (100 %), Chicken (92 %), Rhesus Monkey (100 %)

Produktmerkmale: Rabbit Polyclonal antibody to PI3 kinase p110 gamma (phosphoinositide-3-kinase, catalytic, gamma polypeptide)
PI3K gamma antibody [C3], C-term

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PI3K gamma. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Kommentare:

Positive Control: PI 3-kinase p110gamma tansfected 293T cell , Neuro 2A , C8D30 , Raw264.7

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS, 40 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu PIK3 gamma

Target: PIK3 gamma (PIK3CG) (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))

Andere Bezeichnung: PI3K gamma (PIK3CG Produkte)

Synonyme: PI3CG antikoerper, PI3K antikoerper, PI3Kgamma antikoerper, PIK3 antikoerper, Pi3k antikoerper, wu:fb15d07 antikoerper, zgc:77033 antikoerper, pi3k antikoerper, 5830428L06Rik antikoerper, p110gamma antikoerper, p120-PI3K antikoerper, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma antikoerper, phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma antikoerper, si:rp71-17i16.5 antikoerper, PIK3CG antikoerper, Pik3cg antikoerper, pik3cg antikoerper, si:rp71-17i16.5 antikoerper

Hintergrund: This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias.

Molekulargewicht: 126 kDa

Gen-ID: 5294

Pathways: PI3K-Akt Signalweg, RTK Signalweg, AMPK Signaling, TLR Signalweg, Inositol Metabolic Process, Hepatitis C, VEGF Signaling