PIK3 gamma Antikörper (AA 1-100)

Produktnummer ABIN5542535

Dieser Maus Monoklonal Antikörper detektiert spezifisch PIK3 gamma in ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PIK3 gamma Antikörper (AA 1-100) (ABIN5542535)

Target: PIK3 gamma (PIK3CG) (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PIK3 gamma Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 4B5D2

Produktdetails anti-PIK3 gamma Antikörper

Bindungsspezifität: AA 1-100

Verwendungszweck: PIK3CG Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human PIK3CG (AA: 1-100) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu PIK3 gamma

Target: PIK3 gamma (PIK3CG) (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))

Andere Bezeichnung: PIK3CG

Hintergrund: This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene.

Molekulargewicht: 126.5 kDa

Gen-ID: 5294

UniProt: P48736

Pathways: PI3K-Akt Signalweg, RTK Signalweg, AMPK Signaling, TLR Signalweg, Inositol Metabolic Process, Hepatitis C, VEGF Signaling