WNT5A Antikörper (Wingless-Type MMTV Integration Site Family, Member 5A) (AA 185-213)

Details for Product anti-WNT5A Antibody No. ABIN651869, Anbieter: Anmelden zum Anzeigen
Antigen
  • hWNT5A
  • wnt-5A
  • wnt5a-B
  • WNT5A
  • 8030457G12Rik
  • Wnt-5a
  • Wnt family member 5A
  • Wnt family member 5A S homeolog
  • wingless-type MMTV integration site family, member 5a
  • wingless-type MMTV integration site family, member 5A
  • wingless-related MMTV integration site 5A
  • Wnt signaling ligand
  • WNT5A
  • Wnt5a
  • wnt5a.S
  • wnt5a
  • LOC578814
  • wnt5
Epitop
AA 185-213, Center
18
15
14
14
10
7
5
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
152
60
48
19
18
16
3
3
2
1
1
1
1
1
Wirt
Kaninchen
102
58
2
1
Klonalität (Klon)
Polyklonal ()
Konjugat
Dieser WNT5A Antikörper ist unkonjugiert
8
7
6
4
4
3
3
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
126
64
62
57
16
13
12
5
2
1
1
1
1
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Immunogen This WNT5A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-213 AA from the Central region of human WNT5A.
Klon RB22340
Isotyp Ig Fraction
Spezifität This WNT5A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-221 amino acids from the Central region of human WNT5A.
Homologie Mouse (Murine),Rat (Rattus),Rabbit
Reinigung This antibody is purified through a protein A column, followed by peptide affinity purification.
Andere Bezeichnung WNT5A (WNT5A Antibody Abstract)
Hintergrund The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98%, 98% and 87% amino acid identity to the mouse, rat and the xenopus Wnt5A protein, respectively. The experiments performed in Xenopus laevis embryos identified that human frizzled-5 (hFz5) is the receptor for the Wnt5A ligand and the Wnt5A/hFz5 signaling mediates axis induction. [provided by RefSeq].
Synonyms: Protein Wnt-5a,WNT5A,
Molekulargewicht 42339 DA
Gen-ID 7474
NCBI Accession NP_003383
UniProt P41221
Pathways WNT Signalweg, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Cell Size, Tube Formation
Applikations-hinweise WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit 6 months
Bilder des Herstellers
Western Blotting (WB) image for anti-Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) (AA 185-213), (Center) antibody (ABIN651869) WNT5A Antibody (Center) (ABIN651869) western blot analysis in Hela cell line lysates ...
Immunohistochemistry (IHC) image for anti-Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) (AA 185-213), (Center) antibody (ABIN651869) WNT5A Antibody (Center) (ABIN651869) immunohistochemistry analysis in formalin fixed ...
Flow Cytometry (FACS) image for anti-Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) (AA 185-213), (Center) antibody (ABIN651869) WNT5A Antibody (Center) (ABIN651869) flow cytometric analysis of Hela cells (right hi...
Allgemeine Veröffentlichungen He, Saint-Jeannet, Wang, Nathans, Dawid, Varmus: "A member of the Frizzled protein family mediating axis induction by Wnt-5A." in: Science (New York, N.Y.), Vol. 275, Issue 5306, pp. 1652-4, 1997 (PubMed).

Danielson, Pillarisetti, Cohen, Sholehvar, Huebner, Ng, Nicholls, Cheah, Iozzo: "Characterization of the complete genomic structure of the human WNT-5A gene, functional analysis of its promoter, chromosomal mapping, and expression in early human embryogenesis." in: The Journal of biological chemistry, Vol. 270, Issue 52, pp. 31225-34, 1996 (PubMed).

Smolich, McMahon, McMahon, Papkoff: "Wnt family proteins are secreted and associated with the cell surface." in: Molecular biology of the cell, Vol. 4, Issue 12, pp. 1267-75, 1994 (PubMed).

Clark, Cohen, Eichstetter, Cannizzaro, McPherson, Wasmuth, Iozzo: "Molecular cloning of the human proto-oncogene Wnt-5A and mapping of the gene (WNT5A) to chromosome 3p14-p21." in: Genomics, Vol. 18, Issue 2, pp. 249-60, 1994 (PubMed).

Haben Sie etwas anderes gesucht?