ATP6V0A4 Antikörper (AA 235-261)

Produktnummer ABIN2840303

Produktdetails anti-ATP6V0A4 Antikörper

Target: ATP6V0A4 (ATPase, H+ Transporting, Lysosomal V0 Subunit A4 (ATP6V0A4))

Bindungsspezifität: AA 235-261

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP6V0A4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ATP6V0A4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 235-261 amino acids from the Central region of human ATP6V0A4.

Klon: RB26169

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu ATP6V0A4

Target: ATP6V0A4 (ATPase, H+ Transporting, Lysosomal V0 Subunit A4 (ATP6V0A4))

Andere Bezeichnung: ATP6V0A4 (ATP6V0A4 Produkte)

Synonyme: A4 antikoerper, ATP6N1B antikoerper, ATP6N2 antikoerper, RDRTA2 antikoerper, RTA1C antikoerper, RTADR antikoerper, STV1 antikoerper, VPH1 antikoerper, VPP2 antikoerper, Atp6n1b antikoerper, a4 antikoerper, ATPase H+ transporting V0 subunit a4 antikoerper, ATPase, H+ transporting, lysosomal V0 subunit A4 antikoerper, ATP6V0A4 antikoerper, Atp6v0a4 antikoerper

Hintergrund: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. This gene is one of four genes in man and mouse that encode different isoforms of the a subunit. Alternatively spliced transcript variants encoding the same protein have been described. Mutations in this gene are associated with renal tubular acidosis associated with preserved hearing.

Molekulargewicht: 96386

Gen-ID: 50617

NCBI Accession: NP_065683, NP_570855, NP_570856

UniProt: Q9HBG4

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis, Proton Transport