ATP6V0A4 Antikörper (N-Term)
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- Target Alle ATP6V0A4 Antikörper anzeigen
- ATP6V0A4 (ATPase, H+ Transporting, Lysosomal V0 Subunit A4 (ATP6V0A4))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ATP6V0A4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Kreuzreaktivität
- Maus, Rind (Kuh)
- Kreuzreaktivität (Details)
- Mouse (87 %), Bovine (82 %)
- Produktmerkmale
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Rabbit polyclonal antibody to V-ATPase 116 kDa isoform a4 (ATPase, H+ transporting, lysosomal V0 subunit a4)
V-ATPase 116 kDa isoform a4 antibody [N1N3-2] - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the N-terminus region of human V-ATPase 116 kDa isoform a4. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product ATP6V0A4 Primärantikörper
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- Applikationshinweise
- Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
- Kommentare
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Positive Control: A431 , HeLa , HepG2 , Molt-4 , Raji
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- ATP6V0A4 (ATPase, H+ Transporting, Lysosomal V0 Subunit A4 (ATP6V0A4))
- Andere Bezeichnung
- V-ATPase 116 kDa Isoform a4 (ATP6V0A4 Produkte)
- Synonyme
- A4 antikoerper, ATP6N1B antikoerper, ATP6N2 antikoerper, RDRTA2 antikoerper, RTA1C antikoerper, RTADR antikoerper, STV1 antikoerper, VPH1 antikoerper, VPP2 antikoerper, Atp6n1b antikoerper, a4 antikoerper, ATPase H+ transporting V0 subunit a4 antikoerper, ATPase, H+ transporting, lysosomal V0 subunit A4 antikoerper, ATP6V0A4 antikoerper, Atp6v0a4 antikoerper
- Hintergrund
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This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. This gene is one of four genes in man and mouse that encode different isoforms of the a subunit. Alternatively spliced transcript variants encoding the same protein have been described. Mutations in this gene are associated with renal tubular acidosis associated with preserved hearing.
Cellular Localization: Apical cell membrane, Multi-pass membrane protein - Molekulargewicht
- 96 kDa
- Gen-ID
- 50617
- Pathways
- Sensory Perception of Sound, Transition Metal Ion Homeostasis, Proton Transport
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