ATP6V0A4 Antikörper (AA 53-265)

Produktnummer ABIN1886536

Produktdetails anti-ATP6V0A4 Antikörper

Target: ATP6V0A4 (ATPase, H+ Transporting, Lysosomal V0 Subunit A4 (ATP6V0A4))

Bindungsspezifität: AA 53-265

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP6V0A4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 53 and 265 of human ATP6V0A4

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu ATP6V0A4

Target: ATP6V0A4 (ATPase, H+ Transporting, Lysosomal V0 Subunit A4 (ATP6V0A4))

Andere Bezeichnung: V-ATPase 116 kDa isoform a4 (ATP6V0A4 Produkte)

Synonyme: A4 antikoerper, ATP6N1B antikoerper, ATP6N2 antikoerper, RDRTA2 antikoerper, RTA1C antikoerper, RTADR antikoerper, STV1 antikoerper, VPH1 antikoerper, VPP2 antikoerper, Atp6n1b antikoerper, a4 antikoerper, ATPase H+ transporting V0 subunit a4 antikoerper, ATPase, H+ transporting, lysosomal V0 subunit A4 antikoerper, ATP6V0A4 antikoerper, Atp6v0a4 antikoerper

Hintergrund: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells.V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation.V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain.The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits.The V1 domain contains the ATP catalytic site.The V0 domain consists of five different subunits: a, c, c', c'', and d.This gene is one of four genes in man and mouse that encode different isoforms of the a subunit.Alternatively spliced transcript variants encoding the same protein have been described.Mutations in this gene are associated with renal tubular acidosis associated with preserved hearing.[provided by RefSeq]

Molekulargewicht: 96 kDa

Gen-ID: 50617

NCBI Accession: NP_570856, NM_130841

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis, Proton Transport