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Vimentin Antikörper (Biotin)

VIM Reaktivität: Human IHC Wirt: Maus Monoclonal Biotin
Produktnummer ABIN645827
  • Target Alle Vimentin (VIM) Antikörper anzeigen
    Vimentin (VIM)
    Reaktivität
    • 323
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    Human
    Wirt
    • 184
    • 122
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    Maus
    Klonalität
    • 197
    • 134
    Monoklonal
    Konjugat
    • 189
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    Dieser Vimentin Antikörper ist konjugiert mit Biotin
    Applikation
    • 272
    • 128
    • 97
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    • 93
    • 56
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    Immunohistochemistry (IHC)
    Verwendungszweck
    Mouse Anti-Human Vimentin, Biotinylated
    Kreuzreaktivität (Details)
    Vimentin antibody will recognize most mammalian Vimentin except mouse and rat.
    Produktmerkmale
    Collagen & Extracellular Matrix Proteins
    Immunogen
    Purified Human Vimentin.
    Isotyp
    IgG1
    Top Product
    Discover our top product VIM Primärantikörper
  • Applikationshinweise
    Immunohistochemistry.< div class='ty-product-feature'>< div class='ty-product-feature__label'>Cross Reactivity< div class='ty-product-feature__value'>Vimentin antibody will recognize most mammalian Vimentin except mouse and rat.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
    Konzentration
    1 mg/ml in PBS (after reconstitution).
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C
  • Target
    Vimentin (VIM)
    Andere Bezeichnung
    Vimentin (VIM Produkte)
    Synonyme
    CTRCT30 antikoerper, cb28 antikoerper, vime antikoerper, vim antikoerper, vim1 antikoerper, vim2 antikoerper, VIM antikoerper, Vimentin antikoerper, vim4 antikoerper, vimentin antikoerper, vimentin L homeolog antikoerper, vimentin S homeolog antikoerper, VIM antikoerper, Vim antikoerper, vim antikoerper, vim.L antikoerper, vim.S antikoerper
    Hintergrund

    Target Description: Vimentin expression in human malignant glioma cells depends on cellular density, algorithms of drug delivery and chemo/radio treatment. Vimentin and detyrosinated microtubules provide structural support for the extensive microtentacles observed in detached tumor cells and a mechanism to promote successful metastatic spread. Primary colorectal carcinomas display aberrant expression of vimentin, and have activated Notch and TGFbeta signaling pathways. Vimentin is a strong arterial substrate for transglutaminases. Transglutaminase-mediated vimentin dimerization results in a novel unifying pathway by which vasodilatory and remodeling responses may be regulated. Ablation of vimentin expression inhibits migration and invasion of colon and breast cancer cell lines.< div class='ty-product-feature'>< div class='ty-product-feature__label'>Cross Reactivity< div class='ty-product-feature__value'>Vimentin antibody will recognize most mammalian Vimentin except mouse and rat.

    Pathways
    Caspase Kaskade in der Apoptose
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