CLEC7A Antikörper

Produktnummer ABIN641414

Produktdetails anti-CLEC7A Antikörper

Target: CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CLEC7A Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS)

Verwendungszweck: Mouse Anti-Human Dectin-1

Spezifität: 129-10232 recognizes human Dectin-1, also known as beta-glucan receptor (betaGR), a C-type lectin domain family member. It is a major pathogen pattern-recognition receptor that binds beta-glucans, glucose polymers that form cell-wall components or exopolymers of yeasts, fungi and some bacteria. Beta-glucans have also been used experimentally and therapeutically as immunomodulators that enhance resistance to bacterial, yeast, viral and protozoan infections, as well as tumor formation. Dectin-1 also acts as a co-stimulatory molecule on T-cells to induce their proliferation and is necessary for the TLR2-mediated inflammatory response. It is highly expressed on peripheral blood leukocytes and dendritic cells. Human Dectin-1 has two major (betaGR-A and betaGR-B) and several minor isoforms. betaGR-A and betaGR-B differs by the presence and absence, respectively, of a stalk region. 129-10232 recognizes betaGR-A only.

Aufreinigung: Purified

Immunogen: NIH3T3 cells expressing full length Beta-glucan receptor

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Flow Cytometry

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline pH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C

Details zu CLEC7A

Target: CLEC7A (C-Type Lectin Domain Family 7, Member A (CLEC7A))

Andere Bezeichnung: Dectin-1 (CLEC7A Produkte)

Synonyme: CLEC7A antikoerper, BGR antikoerper, Clecsf12 antikoerper, beta-GR antikoerper, CANDF4 antikoerper, CLECSF12 antikoerper, DECTIN1 antikoerper, Clec7b antikoerper, RGD1565140 antikoerper, C-type lectin domain containing 7A antikoerper, C-type lectin domain family 7, member a antikoerper, CLEC7A antikoerper, Clec7a antikoerper

Pathways: Activation of Innate immune Response