SLIT2 Antikörper

Produktnummer ABIN6293578

Produktdetails anti-SLIT2 Antikörper

Target: SLIT2 (Slit Homolog 2 (Drosophila) (SLIT2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLIT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human SLIT2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:200 - 1:2000

Kommentare:

Fetal lung and kidney, and adult spinal cord, Weak expression in adult adrenal gland, thyroid, trachea and other tissues examined

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20C. Avoid freeze / thaw cycles.

Details zu SLIT2

Target: SLIT2 (Slit Homolog 2 (Drosophila) (SLIT2))

Andere Bezeichnung: SLIT2 (SLIT2 Produkte)

Synonyme: SLIL3 antikoerper, Slit-2 antikoerper, Drad-1 antikoerper, E030015M03Rik antikoerper, E130320P19Rik antikoerper, Slil3 antikoerper, mKIAA4141 antikoerper, Slit antikoerper, slil3 antikoerper, slit-2 antikoerper, slit2-a antikoerper, SLIT2 antikoerper, slit guidance ligand 2 antikoerper, slit homolog 2 (Drosophila) antikoerper, slit guidance ligand 2 S homeolog antikoerper, SLIT2 antikoerper, Slit2 antikoerper, slit2 antikoerper, slit2.S antikoerper

Hintergrund: This gene encodes a member of the slit family of secreted glycoproteins, which are ligands for the Robo family of immunoglobulin receptors. Slit proteins play highly conserved roles in axon guidance and neuronal migration and may also have functions during other cell migration processes including leukocyte migration. Members of the slit family are characterized by an N-terminal signal peptide, four leucine-rich repeats, nine epidermal growth factor repeats, and a C-terminal cysteine knot. Proteolytic processing of this protein gives rise to an N-terminal fragment that contains the four leucine-rich repeats and five epidermal growth factor repeats and a C-terminal fragment that contains four epidermal growth factor repeats and the cysteine knot. Both full length and cleaved proteins are secreted extracellularly and can function in axon repulsion as well as other specific processes. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 169.87 kDa

Gen-ID: 9353

UniProt: O94813

Pathways: Regulation of Actin Filament Polymerization, Regulation of Cell Size, Smooth Muscle Cell Migration